Introduction To Human Physiology For Medical Students
von Shokr, Elsayed
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The cells that make up the bodies of all but the simplest multicellular animals, both aquatic and terrestrial, exist in an "internal sea" of extracellular fluid (ECF) enclosed within the integument of the animal. From this fluid, the cells take up O2 and nutrients; into it, they discharge metabolic waste products. The ECF is more dilute than present-day seawater, but its composition closely resembles that of the primordial oceans in which, presumably, all life originated. In animals with a closed vascular system, the ECF is divided into two components: the interstitial fluid and the circulating blood plasma. The plasma and the cellular elements of the blood, principally red blood cells, fill the vascular system, and together they constitute the total blood volume. The interstitial fluid is that part of the ECF that is outside the vascular system, bathing the cells. The special fluids considered together as transcellular fluids are discussed in the following text. About a third of the total body water is extracellular; the remaining two thirds is intracellular (intracellular fluid).
Dr. EL Sayed Ahmed Mohamed Shokr, prof. of Physiology in Faculty of Medicine, Hail University, KSA. Has worked as a lecturer, assistant and associate professor of Physiology and Medical Physiology in the Faculty of Medicine for 16 years, and 7 years in Clinical Skill lab. Measuring the normal and abnormal of ECG for 25 years.
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