A Nano delivery Approach: Development of Atorvastatin Nanoformulation

von Kalsyan, Rita
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Kalsyan, Rita A Nano delivery Approach: Development of Atorvastatin Nanoformulation
Kalsyan, Rita - A Nano delivery Approach: Development of Atorvastatin Nanoformulation

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Beschreibung

As we aware that Atorvastatin is BCS (Class II) drug and has poor solubility, extreme first pass metabolism and thus has poor bioavailability; on keeping in mind of all that factors we have to select that route which minimize all these effects and such formulation which deliver the drug to brain as much as possible. Hence we select intranasal route it offers direct access of drug to brain through olfactory route and avoid first pass metabolism and is suitable to deliver drugs via nanoformulation and have previously been utilized for enhanced brain delivery. NLC formulation could be able to deliver atorvastatin conveniently by intranasal route. NLC are nano sized delivery systems used to deliver drugs via intranasal route in different disease conditions. Their utility in intranasal route has been well documented. They can be suitably modified for improved retention and can cross mucosal barrier.

Mitwirkende

Autor:
Kalsyan, Rita
Raj, Vinit
Sahdev, Anil K.

Weitere Informationen

Biografie:
Rita Kalsyan: ICP, Greater Noida, India.Anil K Sahdev and Vinit Raj:Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
Sprache:
Englisch
Auflage:
1/2017
Seitenanzahl:
92
Medientyp:
Taschenbuch
Verlag:
LAP Lambert Academic Publishing

Stammdaten

Produkttyp:
Taschenbuch
Verpackungsabmessungen:
0.22 x 0.15 x 0.005 m; 0.186 kg
GTIN:
09783330062467
DUIN:
QQCP3V5T4SL
CHF 47.95
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