The Essential Guide to N-of-1 Trials in Health
Dir gefällt dieses Produkt? Sag's weiter!
Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials.
Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.
Preface.- Introduction.- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences.- N-of-1 trials in medical contexts.- Aggregated N-of-1 trials.- Methodological considerations for N-of-1 trials.- Randomization, allocation concealment and blinding.- Data collection and quality control.- Individual reporting of N-of-1 trials to patients and clinicians.- Assessing and reporting adverse events.- Research ethics and N-of-1 trials.- Statistical analysis of N-of-1 trials.- The economics of N-of-1 trials.- Reporting N-of-1 trials to professional audiences.- Single patient open trials.- Systematic review and meta-analysis using N-of-1 trials.- Where are N-of-1 trials headed?- Index.
Each easy to read chapters written by experts
How-to guides for busy clinicians
"This is a philosophical rethinking of the limitations of randomized controlled trials and the value of cross-over experiments conducted with a single patient. ... This is a book for experienced clinicians who are knowledgeable about current evidence-based treatment modalities and who can objectively recognize when to consider different options for treatment." (Vincent F. Carr, Doody's Book Reviews, January 2016)