The Essential Guide to N-of-1 Trials in Health

von Springer Netherland
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Springer Netherland The Essential Guide to N-of-1 Trials in Health
Springer Netherland - The Essential Guide to N-of-1 Trials in Health

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Beschreibung

N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs.  They have the potential to revolutionize the way clinical medicine is practiced.


Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials.


Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more.  Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.

Weitere Informationen

Anmerkung Illustrationen:
XI, 245 p.
Inhaltsverzeichnis:

Preface.- Introduction.- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences.- N-of-1 trials in medical contexts.- Aggregated N-of-1 trials.- Methodological considerations for N-of-1 trials.- Randomization, allocation concealment and blinding.- Data collection and quality control.- Individual reporting of N-of-1 trials to patients and clinicians.- Assessing and reporting adverse events.- Research ethics and N-of-1 trials.- Statistical analysis of N-of-1 trials.- The economics of N-of-1 trials.- Reporting N-of-1 trials to professional audiences.- Single patient open trials.- Systematic review and meta-analysis using N-of-1 trials.- Where are N-of-1 trials headed?- Index.

Herausgeber:
Nikles, Jane;Nikles
Mitchell, Geoffrey;Mitchell
Bemerkungen:
Stand alone chapters covering every aspect of N-of-1 trials


Each easy to read chapters written by experts


How-to guides for busy clinicians

Medientyp:
Buch gebunden
Verlag:
Springer Netherland
Rezension:

"This is a philosophical rethinking of the limitations of randomized controlled trials and the value of cross-over experiments conducted with a single patient. ... This is a book for experienced clinicians who are knowledgeable about current evidence-based treatment modalities and who can objectively recognize when to consider different options for treatment." (Vincent F. Carr, Doody's Book Reviews, January 2016)

Sprache:
Englisch
Auflage:
1st ed. 2015
Seitenanzahl:
245

Stammdaten

Produkttyp:
Buch Gebunden
Verpackungsabmessungen:
0.232 x 0.167 x 0.028 m; 0.717 kg
GTIN:
09789401771993
DUIN:
AA0ELJPOGQ7
CHF 145.85
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