Application of Self-assembled Monolayers to Cholesterol Biosensor

von Arya, Sunil Kumar
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Arya, Sunil Kumar Application of Self-assembled Monolayers to Cholesterol Biosensor
Arya, Sunil Kumar - Application of Self-assembled Monolayers to Cholesterol Biosensor

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Beschreibung

A biosensor is an integrated bioanalytical device that employs biological elements, as analyte sensor, coupled to a transducer for signal detection. Biosensor provides sensitive and selective determination of various compounds of analytical relevance. Recently, use of self-assembled monolayer (SAM) is gaining attention as biosensor matrix. SAM provides a simple route to functionalize electrode surfaces for biosensor fabrication. The alarming rise in the rates of heart diseases due to abnormal levels of cholesterol in blood has stimulated public concern about the estimation of cholesterol level in desired sample. The present book highlights the preparation, characterization and application of some SAMs for immobilization of cholesterol oxidase, cholesterol esterase & horseradish peroxidase for development of cholesterol biosensor. The fabricated bioelectrodes were tested for various parameters like pH, temperature, interferents etc. and have been utilized for free and total cholesterol estimation in solution & serum samples. The results indicate that the SAMs are likely to provide useful matrices for the fabrication of commercial cholesterol sensing bioelectrodes.

Mitwirkende

Autor:
Arya, Sunil Kumar
Datta, Monika
D. Malhotra, Bansi

Weitere Informationen

Biografie:
Dr Sunil Kumar Arya has received BSc (Chemistry), MSc (Organic Chemistry) and PhD (Chemistry-Biosensor) from University of Delhi and has published about 28 papers in international journals. At present, he is working as a PostDoc on MEMS based electrochem. biosensor for biomarkers (Cortisol, PSA) detection at University of South Florida, Tampa, USA.
Sprache:
Englisch
Seitenanzahl:
176
Medientyp:
Taschenbuch
Verlag:
LAP Lambert Academic Publishing

Stammdaten

Produkttyp:
Taschenbuch
Verpackungsabmessungen:
0.22 x 0.15 x 0.01 m; 0.308 kg
GTIN:
09783843352826
DUIN:
423LHM4PD3O
CHF 69.35
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